Be Curious, Not Judgmental

Ruminations and musings about healthcare AI, technology, and strategy

Tag: Startups

  • A Year of Talking to Computers

    A Year of Talking to Computers

    ·

    ,

    I built four iOS apps in the last month. Orbit, a personal CRM Visit Notes, an AI scribe Mosaic, an Apple Watch explorer Curator, a photo album app They’re not masterpieces. They’re real enough to be useful, real enough to be a little embarrassing in places, and real enough to teach me (again) that software is mostly an endless series of small decisions. I’m still slightly surprised that this is… Read more

  • AI and the Prepared Mind: Engineering Luck in Drug Discovery

    ·

    ,

    We are at a fascinating, paradoxical moment in the history of medicine. We stand in awe of a new AI-powered “Logic Engine” for drug discovery—a computational marvel like AlphaFold, which treats biology as an information system to be engineered. It promises a future of rational discovery. And yet, when we look at our most important medical breakthroughs, so many were not rationally designed. They were the result of messy, unpredictable,… Read more

  • AI Can’t “Cure All Diseases” Until It Beats Phase 2

    ·

    ,

    One of the big dreams of AI researchers is that it will soon solve drug discovery (as I explored in AI drug discovery and engineering serendipity) and unleash a boom in new life-saving therapies. Alphabet committed $600 million in new capital to Isomorphic Labs on that rhetoric, promising to “cure all diseases” as its first AI‑designed molecules head to humans next year. And the first wave of AI molecules is moving… Read more

  • The Ricky Bobby School of Strategy

    The Ricky Bobby School of Strategy

    ·

    If you ain’t first, you’re last Ricky Bobby, Talladega Nights: The Ballad of Ricky Bobby Talladega Nights is an old Will Ferrell comedy (also starring Sacha Baron Cohen of Borat fame) about a NASCAR racer who loses his mojo after a crash and learns to regain his passion again after connecting more deeply with friends and family. Ricky Bobby’s estranged father imparts the above words of racing wisdom to an… Read more